Protein Details: Glutamate receptor 3.7

Protein ID

ICDB_Pro_1628

Protein Name

Glutamate receptor 3.7

Gene Name

GLR3.7; GLR5; At2g32400; T32F6.8

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

921 amino acids

AlphaFoldDB

AF-Q9SDQ4-F1-model_v4.pdb

Function

Glutamate-gated receptor that probably acts as a non-selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells.

Sequence

MGLGIDPSVAITALIVVILVVPMDCQRPQLVNIGAVFAFDSVIGRAAKVALEAAVSDVNNDKSFLKETELRLLMEDSACNVFRGSFGAFELLEKEVVAMIGPISSSVAHTISDIAKGLHFPLVSFAATDPTLSALQFPFFLRTTPNDAHQMSALVDLINFYGWKEVISVYSDDELGRNGVSALDDELYKKRSRISYKVPLSVHSDEKFLTNALNKSKSIGPRVYILHFGPDPLLRIFDIAQKLQMMTHEYVWLATDWLSVTLDSLSDKGTLKRLEGVVGLRQHIPESVKMEHFTHKLQSNRSMNAYALHAYDTVWMIAHGIEELLNEGINITFSYSEKLLHARGTKLHLEKIKFFNSGELLLEKLLKVNFTGIAGQVQFGSGRNVIGCDYEIINVNKTDVHTVGFWSKNGGFSVVAPKTRHSQKKTSFVSDEKLGDITWPGGGREKPRGWVIADSADPLKIVVPRRVSFVEFVTEEKNSSHRIQGFCIDVFIEALKFVPYSVPYIFEPFGNGHSSPNYNHLIQMVTDGVYDAAVGDIAIVPSRSKLVDFSQPYASTGLVVVIPANDDNATWIFLRPFTSRLWCVVLVSFLVIAVVIWILEHRINEDFRGPPRRQLSTMLLFSFSTLFKRNQEDTISNLARLVMIVWLFLLMVLTASYTANLTSILTVQQLPSAITGIDSLRASEVPIGYQAGTFTLEYLTYSLGMARSRLVPLDSTEEYEKALKLGPTNWGGVAAIVDELPYIELFLAERTGFKIVGEPFMHRGWGFAFKRDSPLAIDMSTAILKLSETRKLQEIRKKWLCKTNCAGKSNWNPEPNQLHLKSFKGLYLVCIAITVSAFLVFVLRMIRQFVRYRRMERTSSMPRASWSASPTLRLRELVFDFVEFVDEKEEAIKRMFRRSDDSNNNPSHVGEVQADTEVPRN

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Expressed predominantly in leaves and siliques. Also detected in roots.

DOI ID

10.1126/science.292.5521.1486b; 10.1038/45471; 10.1111/tpj.13415; 10.1093/oxfordjournals.molbev.a004165

RefSeq

NP_565744.1